hCELA3B, His-Tag; inactive variant S217A Pseudomonas aerigunosa It is the major processing

It is the major processing enzyme of the secretory pathway and is localized in the trans-golgi network where it functions to cleave other proteins into their mature/active forms

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Nature (2021)

: P2020-128

hCELA3B, His-Tag; inactive variant S217A Pseudomonas aerigunosa It is the major processingThe elastase 3B is relative to pancreatic serine proteinases and has a low level of elastolytic activity comparing to other elastases. Elastase 3B is probably involved in the intestinal transport and metabolism of cholesterol. Furthermore, elastase 3B is an efficient protease that preferentially cleaves proteins after alanine residues due to its alanine specificity. Both elastase 3A and elastase 3B have been referred to as protease E and elastase 1.